He said, “Indeed, my hand is lifted up toward the LORD’s throne. The LORD will be at war with Amalek from generation to generation.” Exodus 17:16 (HCSB) 

The Amalekites were the persistent and relentless enemies of the Israelites. When the Israelites sought to enter the Promised Land, the Amalekites stood in their way (Exod. 17:8–16). Once the Israelites were in the Promised Land and seeking to enjoy what God had given them, the Amalekites joined the Midianites to torment the Hebrews in the days of Gideon.
Whenever the Israelites planted crops, the Midianites, Amalekites, and the Qedemites came and attacked them. Judges 6:3 (HCSB)
It was an Amalekite that caused the downfall of King Saul.
Saul and his men spared Agag’s life and kept the best of the sheep and goats, the cattle, the fat calves, and the lambs—everything, in fact, that appealed to them. They destroyed only what was worthless or of poor quality. ... And Samuel said to him, “The LORD has torn the kingdom of Israel from you today and has given it to someone else—one who is better than you. 1 Samuel 15:9,28 (NLT) 
The Amalekites continually sought to hinder the progress of God's people and to rob them of God's blessing. Thus God swore His enmity against them for eternity.
Beware of the Amalekites!


As you move forward in your pilgrimage with the Lord, there will be “Amalekites” that will seek to distract and defeat you. God is determined to remove anything that keeps you from experiencing Him to the fullest. If your commitment to your job is keeping you from obedience to Him, God will declare war against it. If a relationship, materialism, or a destructive activity is keeping you from obeying God's will, He will wage relentless war against it. There is nothing so precious to you that God will not be its avowed enemy if it keeps you from His will for your life. King Saul mistakenly thought he could associate with Amalekites and still fulfill the will of the Lord.
He captured Agag, the Amalekite king, but completely destroyed everyone else. Saul and his men spared Agag’s life and kept the best of the sheep and goats, the cattle, the fat calves, and the lambs—everything, in fact, that appealed to them. They destroyed only what was worthless or of poor quality. 1 Samuel 15:8-9 (NLT) 
You may also be hesitant to rid yourself of that which causes you to compromise your obedience to God. Don't make the same mistake as King Saul. He did not take the Amalekites seriously enough, and it cost him dearly.

© EGDD